Maria and Loukas decide at the same time and for no apparent reason to respectively run away from their homes. Each of them has to deal with their personal problems: Maria is stuck in a wealthy marriage with Dimitris while raising their two children. Loukas is unemployed and full of debts. Both of them run away from their personal issues, both of them begin wandering in modern day Athens. They come across a series of controversial events and meet with strange characters. Furthermore, various people seem to be on their track; Maria is followed by two policemen. Loukas is followed by a weird stranger dressed in black, Joseph, who desperately wants something from him.

The Runaway Day is a black and white 16mm film based on familiar patterns of b-movies and aims to portray the despair felt by modern Greeks in contemporary Athens, a city that is in full decay . That same feeling seems to feel and the Athenians while stifling and increasing pressure leads to a mass exodus , a pandemic character escape to an unknown destination . Beyond the irresistible tendency to run away , the next effect that the phenomenon has to the residents of the city is to bring to the fore the deepest and most untold desires. As the spiral of the film΄s story unfolds , it comes to the foreground the dreary environment where Runaway Day takes place : Athens , a once beautiful city, collapses progressively along with the western culture.