Serkan Zelzele has started his carrier, designing scriptable motion graphics used in such movies: My Best Friend's Wedding (1997), As Good as It Gets (1997), Face/Off (1997), where he designed, futuristic panels and created facial and body transformations for actors Nicholas Cage and John Travolta.

Till then, he has worked on various movies like Superman Returns (2006), The Chronicles of Narnia: The Lion, the Witch and the Wardrobe (2005), Harry Potter and the Sorcerer's Stone (2001), X2 (2003),  Titanic (1997) - Academy Award for Best Visual Effects. 

His last works before co-founding Epics Fx Studios Mexico; sequence supervised The Mummy: Tomb of the Dragon Emperor (2008), Night at the Museum: Battle of the Smithsonian (2009),  where he was responsible for the sequence had a giant computer generated slimy Octopus, cg Abraham Lincoln Memorial and a full cg animated Abraham Lincoln statue.

He has recently served as a Visual Effects Supervisor for Day After Disaster (2009), creating photo realistic nuclear explosion scenery; destroying Washington DC with sophisticated dynamic simulation technology, and creating city's aftermath with various matte painting and compositing techniques.